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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28b4ddc87cb2d44ae30db3ee6a3696b16e7a201e398b141dd39c3882144ef905' 
  AND token = 'YekxUws/uQSu9g/LDu9B+LvVS0DAi6kKyPh4k+zKETY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}