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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac99a620208611a03ee25dfdb436d1bea17477f3ce6f96412dd87adbb3325a58' 
  AND token = 'IhnIxLrpGjMAtWUzWZF2iqZrFCDztp0IJ3YrC/6EE5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}