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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14010af647ea7b67a39b0c5762d8e9c6c983d99c9e7ea294ae49b6f12fb46fff' 
  AND token = 'FWZ8jM8W80dSr9UFiNoJjXQaICvz31Um6K2dp3VvXng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}