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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f80feb0fc5b959e8e3816e39b2e70b0f193b3841d457620a7d0759bb791aa3e' 
  AND token = '4x9BmWyqHU3suTjh7ajW5KrHZ+vhfxQW4v1nuzsXSrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}