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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78b07c73a21f87c77bc2f0abdfce50a532c8331c9721714296dd0b02baa574c' 
  AND token = 'IeDImjtGSrVBW1lJz1F0SFUQo+hjrZSdoN55aPbxBBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}