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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d410d816edf56e5959b6bb1677ade67c9d6f437c230739186132d5227ecaca3' 
  AND token = 'sxBhbkGNJxgkxWrwauFF3idWBwb1A4zKBqDziaMC+lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}