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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '756cca3297c3a324985e9c8dc8e212e37d2394d62092351de1ffc7cf5e852ccc' 
  AND token = '//S5m5ZKikoTRJwRGya9YMOXGgwVGBf5WSr9/xoNZpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}