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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cfdbe65034041e61419a6c28ef4e7dd0c4b0f4250ab3ccdbf834a5860876c5e' 
  AND token = 'FL/Oh6PzjY2jySR85qoIXNw2E5xNbNoLNHsvj1TdyZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}