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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64533a19b5d3e6a79e657cc389c61ee17e8e3291ed8013faa8ec039807d42577' 
  AND token = 'jc29MfMsgSRRSQNwv7FKPcEqV334oQbXfU+H7UUgoGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}