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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4523209726258e301dab50a207b1d56e4f1eef50d829cd2552c1391f7b04d8cd' 
  AND token = '/6sFY4pm7rGH4WlSczC9diDPeL/yG/f7B4iRX2m4g4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}