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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd43c785ef6e1e543ecc887f37ccf2567cfea1df218bf1da6e211347f836cbc74' 
  AND token = 'EapvVPEyXyyMOfhTSL5aga2mdO7uRhxg9eblUlw/++0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}