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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aa4aa0d5f9c54990674cdadfc08ca88ad35a4012ccc371ddd4bf6e06ec5f112' 
  AND token = 'EgSSY/lVJ+aVM4CZJ4fyei/1r8UxKiOI9hkY+5kmOXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}