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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '821f77b6b16bcaf27f4821bff3e6c5cc490cfb24148ad3c7fcb2221bf9f38c55' 
  AND token = '06kdCwcy74EwXB03bdBwMc1jDQ4zQxMx8vFgDKb2dC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}