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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d8f794e2fb8274b20c371e23ffe70dac85b749d20e54f2f1e1bd96ebe14b945' 
  AND token = 'UM8Sqro7LQSKIbdEYA1Fg3NAPgLlcd0WPkKTFiB+TT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}