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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c95b1238516206ceb824d6d3f01729b5abc3b6fd314b521a00cd1e5fe875f628' 
  AND token = '+jctHnSGq14LMiGPngPqOYYnbwliXt1dl9T0F75ckes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}