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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0af5aa44244e49b81cabe6981b1a0bb7c6c4b47e5ccd21551e8953d4edfc43ff' 
  AND token = 'ZGOFVUXLkrp+LiKgGsIGnUdxc0JneSLrTG8llFp8KdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}