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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c21bb03c4c2a15294fc6aff62ea95ee77340c2d4a5e562fbfd1f973e2e09218' 
  AND token = 's+EAht+dKHE5DA5w1ixjZSKDvgsICS28hqn1wyIKvbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}