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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6678dca4ff83b64dd88ec1c66b32a10d6336667f7005e4edf440532f402c2a1e' 
  AND token = 'oMLokvf5C+hI5Fhe0+HTJXZ0j/BtZXYtbENpqvhOF40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}