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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ce2de6340e0747ecb711dc495b0481b767b49d3b328ca15b4caaab63849fea6' 
  AND token = 'eAE0cxNl/ql0zS2vUOt7erl8iUnSbEzcMAWl21Gnng8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}