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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5f723fd7eae4d594ddbd2606c4ed5139b38f359cac6a8d4e2a545b878db028b' 
  AND token = 'Ba6HvNFRn2zpOd+EZMqy22jOUrcRGDkDW0rve5Ss1Rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}