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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '264da2dc007bf51a3630689904be51990bd940a3ff816c8dd6ef55668c4df6ee' 
  AND token = 'h9Q+Cafk74LZ1O2DVX0iICOzPz4XTKTBxhfzLD87bLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}