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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f5028c18f6a31a9dcba77cd1abcb75183cfb176a60d7203a3beba663a6b0b6b' 
  AND token = 'hmJRnh2prvFrn++SGdPGEPHqjyb0tZVDtbkl/yNhGwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}