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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e121954c995c11e0dc90bbca0990132413e7583f7bf024d4287fcf8dc8534b8' 
  AND token = 'eqkh4E3CYEzdTrHWxySnVGPLKrmFk3/7vzTDrjkCXwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}