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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd67971099e913bb58ce0042e4a9f4d1212d7b57dd6233486da5ad647060e9422' 
  AND token = '1DV531u1c04G2c3YOeN1AFKKy9pNhEXe5qJmCqLuNLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}