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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e75a128b6b0bba819b29d258cf345bd7f41aa5c6a2895c20bc32b1ad227b3815' 
  AND token = 'Nb4pQAcN+WEbOpKSk6vgTG7hA3wg1OCE+M4n4WdXqlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}