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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0fa06865103f6512f98fb86823cf584e435c0ba13dd17d747dd9f06d23cecc1' 
  AND token = 'vrTZ+oJJk0AifTYcJo0MRmf5L4MXcyhDJtgyCl9RTqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}