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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5892519720af578039df39e87be86dfd385d43d3527e2e4732c9ce64d52b1214' 
  AND token = 'qqikJ2sdlxF/yt/XJwvo1b4H6FwzOMrvx4CtWaTaCnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}