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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65acedc052ecfbb6c25f1430be88d0c6df3297670e6de3252c32d13f73c367d7' 
  AND token = 'nBOltJbD2BJBgpS82dLALemXRYDzU7iaJOR703X04fA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}