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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14e032a260fc3c68b7240072faba90064716abed6af4f1a5c12bdb04adfa82e8' 
  AND token = 'kjc6hoFCDcN2IbsjER9ia0z+VzT+UzOa4eUj+lWhXuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}