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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c2f18c739da0b5838ba769b2624b34619b2f08eaa1c769e1856d8ecb265104e' 
  AND token = 'u2Aw0CzCap+ci6MpK7TglYDV41Gwn6lSnvHGgMdoHXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}