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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99548fe7cb7d0c8435e03ae2f9aa7d0d78578e174bf9c755e177274458ec6796' 
  AND token = 'z8QHVJI3I66IkK2IvGit3LNn28AokBKRwYqGUA5Qbu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}