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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6c98afbfa45d754437843878e100284ef4f3e62b44e2b47d9be9e2a412a5902' 
  AND token = 'IHAE1lDvI8kz0VJ+2wiDD92we4anIeb4WWAivBtvUxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}