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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11aa9a6b6389fcd6ac4eca6376449efd8c13627c61710ab0256bb640ad4f1e52' 
  AND token = 'gFVorSdXsYcdIRyps3/6nEAVzH3NLo4NCy4yKAzzZHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}