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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2def03c0a283934a2ef49bd775a5ac934ff571663c257a44eb7da0ae5b7712ac' 
  AND token = 'iLMAEO9h6ejglzB6R8JIlb/+nMt5b4zle5KdhTW34lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}