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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4bd10229d88615abe2e346167351d6a92d981ce927979574d8386daf33c1aa1' 
  AND token = 'KJEWgS3u249E+wDkQpJxYSIbL26AdZY5YzXNePUC1Eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}