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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b09a99e98cdf4726b90165f514c85d6f049bf20487a03f39345c88eacfa32282' 
  AND token = 'UzHHDN8qaj+t1APmKdS5LPwRNKgYSfH2oIn4heXoOYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}