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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f104fbf676b8db67def1c244ea616a25f9c82ec3ab99f6858a7a325878419d6' 
  AND token = 'i4coMsO8/VwaQ1XoF9cLE17E+LlNbx02iZ+zxxTtfZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}