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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb973b002000b8adcd6c4f51d20c60a90952cdf8ae21a677bb66a69c8d631f0c' 
  AND token = 'zo3awoputchbNh+D/ERllXzwIVoPktAmkU89vj5u100=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}