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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '922299e05557a1e57c239fe4e38b9fd774870978a6b2a78472eec0ca0a26f130' 
  AND token = '1smWW0j88uAPEjDx8c7B2vmDhRRgGKMBaG/AV+W9Y6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}