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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6685d216e9ecf41bd6c876c2fdb2f116e52b69a35333c1b61ff605e76f08c1b4' 
  AND token = 'EfRZzVdcokBJTgefJXJvz4fhRLj5iWSmUoIOoH58/20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}