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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a6d0cf227d522e3aac0ae8b6e4679befae808fbfedca2db15a898d82f8ae5bf' 
  AND token = 'o9wViU7Qvf30ZSjxXDM3xkvZQjcbZccyMbJSSMR1EAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}