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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eb6b23d242351508ea3decb20f9245bcd396f514fa5c2af77345e6074190662' 
  AND token = 'ZIEPPjPn6XJc3jNRmq08wySGeA7hGfvdfO0w0WkDbJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}