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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2c1c0a2afc9bc099df35b31aaf63c55b4e7b3dd12fddb3a4b4de614335006e0' 
  AND token = 'md+an7aHFIO+kgtNzpotr8j6kQDYUMangn4AXRpNqUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}