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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8326b24bb06b552b2b199b2134be779d2dcc0b019951c251724b8dfbe3e57245' 
  AND token = 'bdN90uurW2ZkVHySMtjUS+ODe6KJ8MshiEwdZiekwc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}