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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b593e1588dc70b9f5917338eed2c1d2231bbb8482872f1de54ce168a6721497' 
  AND token = 'm2Btr3nQzhGA2qRpRWtWvCzEp2/xbzo1T9PWxOF5Nyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}