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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0de849342f748f85c94df88084449fa270d1f05f14dcab73ba5d9c786e8c9ce7' 
  AND token = '03M8QhOwpSRFlQxDhyaNeQwm6AuiaoGma1c5A+j0PnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}