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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80ae73c52e98d86b084d263c2d2821cd131ef76fbc748288caddd46c38123dec' 
  AND token = 'hhW4qJlfquJpuBiv0amm3/pUcoagiybdVV5ajlOqwek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}