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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a428425eb1c0eea26bce42d55a0e9ed65a187810f4928e76066bad81d70a88ba' 
  AND token = 'iHRwzXfA03+F67F6/D5AbLaDuq3ta9/QI6oV26Kipfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}