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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39ba1c59129475641a4d0d41b94761cd7137fb666cddee36f36849778f43962e' 
  AND token = 'ci/s3x5Azs18st7cJEPHV6NeaBKtq9GrWOrBvSDcHDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}