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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20449b2fe1dc364cb6effa462369b809ff1c7cfe3cfaaa0bcf14600984e1eca1' 
  AND token = 'orkxzyQeZUU/sNMdSqyOL/rlyGjd/o1Zbbp+7zjGss0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}